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Article

Forward-time simulation of realistic samples for genome-wide association studies.

BMC bioinformatics - 1 Sept 2010

Peng Bo, Amos Christopher I

Abstract excerpt

BACKGROUND: Forward-time simulations have unique advantages in power and flexibility for the simulation of genetic samples of complex human diseases because they can closely mimic the evolution of human populations carrying these diseases. However, a number of methodological and computational constraints have prevented the power of this simulation method from being fully explored in existing forward-time...

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Identifiers

PMID: 20809983
DOI: 10.1186/1471-2105-11-442
PMCID: PMC2939614

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