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Article

An overview of population genetic data simulation.

Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 2012

Yuan Xiguo, Miller David J, Zhang Junying, Herrington David, Wang Yue

Abstract excerpt

Simulation studies in population genetics play an important role in helping to better understand the impact of various evolutionary and demographic scenarios on sequence variation and sequence patterns, and they also permit investigators to better assess and design analytical methods in the study of disease-associated genetic factors. To facilitate these studies, it is imperative to develop simulators with the...

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Identifiers

PMID: 22149682
DOI: 10.1089/cmb.2010.0188
PMCID: PMC3244809

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