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Article

Susceptibility to sequelae of human ocular chlamydial infection associated with allelic variation in IL10 cis-regulation.

Human molecular genetics - 15 Jan 2008

Natividad Angels, Holland Martin J, Rockett Kirk A, Forton Julian, Faal Nkoyo, Joof Hassan M, Mabey David C W, Bailey Robin L, Kwiatkowski Dominic P

Abstract excerpt

Trachoma, an infectious disease of the conjunctiva caused by Chlamydia trachomatis, causes scarring and blindness in some infected individuals but not others. In an African community where trachoma is endemic, we have previously identified an IL10 haplotype that is associated with increased risk of scarring complications. Here we examine the hypothesis that the risk haplotype (H-RISK) affects levels of IL10...

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PMID: 17947295
DOI: 10.1093/hmg/ddm310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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