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Article

Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.

BMC medical genetics - 16 Dec 2009

Natividad Angels, Hull Jeremy, Luoni Gaia, Holland Martin, Rockett Kirk, Joof Hassan, Burton Matthew, Mabey David, Kwiatkowski Dominic, Bailey Robin

Abstract excerpt

BACKGROUND: Trachoma, a chronic keratoconjunctivitis caused by Chlamydia trachomatis, is the world's commonest infectious cause of blindness. Blindness is due to progressive scarring of the conjunctiva (trachomatous scarring) leading to in-turning of eyelashes (trichiasis) and corneal opacification. We evaluated the contribution of genetic variation across the chemokine and cytokine clusters in chromosomes 4q and...

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Source

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Identifiers

PMID: 20015396
DOI: 10.1186/1471-2350-10-138
PMCID: PMC2810293

Genes

CSF2
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.PMID 20015396Read ↗

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