Article
Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3.
PLoS neglected tropical diseases - 1 Mar 2014
Roberts Chrissy H, Molina Sandra, Makalo Pateh, Joof Hassan, Harding-Esch Emma M, Burr Sarah E, Mabey David C W, Bailey Robin L, Burton Matthew J, Holland Martin J
Abstract excerpt
BACKGROUND: Chlamydia trachomatis is globally the predominant infectious cause of blindness and one of the most common bacterial causes of sexually transmitted infection. Infections of the conjunctiva cause the blinding disease trachoma, an immuno-pathological disease that is characterised by chronic conjunctival inflammation and fibrosis. The polymorphic Killer-cell Immunoglobulin-like Receptors (KIR) are found...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
