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Article

Association of single nucleotide polymorphisms of interleukins-1β, -6, and -12B with contact lens keratitis susceptibility and severity.

Ophthalmology - 1 Jul 2012

Carnt Nicole A, Willcox Mark D P, Hau Scott, Garthwaite Linda L, Evans Victoria E, Radford Cherry F, Dart John K G, Chakrabarti Subhabrata, Stapleton Fiona

Abstract excerpt

PURPOSE: To investigate whether single nucleotide polymorphisms (SNPs) in interleukin (IL)-1β, IL-6, and IL-12β are associated with the susceptibility and severity of contact lens-related keratitis. DESIGN: Retrospective, case control study. PARTICIPANTS: One hundred twelve cases of keratitis and 225 controls were recruited from studies conducted at Moorfields Eye Hospital and in Australia during 2003 through...

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PMID: 22503230
DOI: 10.1016/j.ophtha.2012.01.031

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