Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatis infection.

BMC medical genetics - 27 Apr 2006

Natividad Angels, Cooke Graham, Holland Martin J, Burton Matthew J, Joof Hassan M, Rockett Kirk, Kwiatkowski Dominic P, Mabey David C W, Bailey Robin L

Abstract excerpt

BACKGROUND: Trachoma, an infectious disease of the conjunctiva caused by Chlamydia trachomatis, is an important global cause of blindness. A dysregulated extracellular matrix (ECM) proteolysis during the processes of tissue repair following infection and inflammation are thought to play a key role in the development of fibrotic sequelae of infection, which ultimately leads to blindness. Expression and activity of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Chlamydia trachomatis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cicatrix

Share to Haplotypes

Share to Matrix Metalloproteinase 9

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 16643654
DOI: 10.1186/1471-2350-7-40
PMCID: PMC1513383

Genes

MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatis infection.PMID 16643654Read ↗

Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.Semantic proximity Read ↗

Risk of trachomatous scarring and trichiasis in Gambians varies with SNP haplotypes at the interferon-gamma and interleukin-10 loci.Semantic proximity Read ↗

Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis.Semantic proximity Read ↗

Polymorphisms in Candidate Genes and Risk of Scarring Trachoma in aChlamydia trachomatis–Endemic PopulationSemantic proximity Read ↗

Genetic variation at the TNF locus and the risk of severe sequelae of ocular Chlamydia trachomatis infection in Gambians.Semantic proximity Read ↗

Studies on the development of scarring trachoma in TanzaniaSemantic proximity Read ↗

Population-based analysis of ocular <i>Chlamydia trachomatis</i> in trachoma-endemic West African communities identifies genomic markers of disease severitySemantic proximity Read ↗

Conjunctival MicroRNA Expression in Inflammatory Trachomatous ScarringSemantic proximity Read ↗

Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity.Semantic proximity Read ↗

Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study.Semantic proximity Read ↗

miRNAs that associate with conjunctival inflammation and ocular Chlamydia trachomatis infection do not predict progressive disease.Semantic proximity Read ↗

Susceptibility to sequelae of human ocular chlamydial infection associated with allelic variation in IL10 cis-regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.