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Article

Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis.

PloS one - 1 Jan 2008

Atik Berna, Skwor Troy A, Kandel Ram Prasad, Sharma Bassant, Adhikari Him Kant, Steiner Lori, Erlich Henry, Dean Deborah

Abstract excerpt

BACKGROUND: Trachoma is the leading preventable cause of global blindness. A balanced Th1/Th2/Th3 immune response is critical for resolving Chlamydia trachomatis infection, the primary cause of trachoma. Despite control programs that include mass antibiotic treatment, reinfection and recurrence of trachoma are common after treatment cessation. Furthermore, a subset of infected individuals develop inflammation and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18974840
DOI: 10.1371/journal.pone.0003600
PMCID: PMC2572999

Genes

VCAM1
LTA
ICAM1
VDR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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