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Article

Production and characterization of transgenic mice systemically expressing endo-beta-galactosidase C.

Glycobiology - 1 Jan 2008

Watanabe Satoshi, Misawa Masako, Matsuzaki Takashi, Sakurai Takayuki, Muramatsu Takashi, Yokomine Taka-Aki, Sato Masahiro

Abstract excerpt

The alphaGal epitope (Galalpha1-3Gal) is a sugar structure expressed on the cell surface of almost all organisms except humans and old-world-monkeys, which express natural anti-alphaGal antibodies. The presence of these antibodies elicits a hyper acute rejection (HAR) upon xenotransplantation of cellular materials, such as from pigs to human beings. Endo-beta-galactosidase C (EndoGalC), an enzyme isolated from...

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PMID: 17947256
DOI: 10.1093/glycob/cwm114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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