Article
Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype.
PloS one - 1 Jan 2016
Gladh Hanna, Folestad Erika Bergsten, Muhl Lars, Ehnman Monika, Tannenberg Philip, Lawrence Anna-Lisa, Betsholtz Christer, Eriksson Ulf
Abstract excerpt
Platelet-derived growth factor D (PDGF-D) is the most recently discovered member of the PDGF family. PDGF-D signals through PDGF receptor β, but its biological role remains largely unknown. In contrast to other members of the PDGF family of growth factors, which have been extensively investigated using different knockout approaches in mice, PDGF-D has until now not been characterized by gene inactivation in mice....
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