Sequence‐Based Human Leukocyte Antigen–B Typing of Patients Infected with Ebola Virus in Uganda in 2000: Identification of Alleles Associated with Fatal and Nonfatal Disease Outcomes

Abstract excerpt

The Sudan species of Ebola virus (SEBOV) causes severe, often fatal infection in approximately 50% of infected humans. We sought to determine whether the human leukocyte antigen-B (HLA-B) locus has a role in the outcome of SEBOV disease by typing 77 cases from an outbreak in northern Uganda in 2000-2001. Sequence-based HLA-B typing was performed using leukocytes isolated from 77 patients. Statistical analysis and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hepatitis B Virus Studies
• Share to Viral Infections and Outbreaks Research
• Share to Virology and Viral Diseases