Article
Distribution of HLA-B alleles in a Ugandan HIV-infected adult population: NORA pharmacogenetic substudy of DART.
Tropical medicine & international health : TM & IH - 1 Feb 2011
Munderi Paula, Snowden Wendy B, Walker Ann Sarah, Kityo Cissy, Mosteller Michael, Kabuye Geoffrey, Thoofer Navdeep K, Ssali Francis, Gilks Charles F, Hughes Arlene R
Abstract excerpt
OBJECTIVES: To determine the frequencies of HLA-B alleles in Ugandan patients in the NORA substudy of the DART trial and to compare HLA-B allele frequencies in those with and without clinically diagnosed hypersensitivity reaction (HSR). METHODS: DNA-based HLA-B genotyping was used to determine HLA alleles in 247 participants who received abacavir, including all six participants ('cases') with clinically diagnosed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
