Article
HLA class I allele and haplotype diversity in Ugandans supports the presence of a major east African genetic cluster.
Tissue antigens - 1 Mar 2009
Kijak G H, Walsh A M, Koehler R N, Moqueet N, Eller L A, Eller M, Currier J R, Wang Z, Wabwire-Mangen F, Kibuuka H N, Michael N L, Robb M L, McCutchan F E
Abstract excerpt
The objective of this study was to characterize the class I human leukocyte antigen (HLA) genetic composition of the Ugandan population to better define its relationship with other African groups. Samples from 175 individuals from Kampala (Uganda) were subjected to class I HLA-A, -B, and -C sequence-based typing. The high concordance between the major alleles and haplotypes found in the current and Kenyan...
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