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Article

High-throughput high-resolution class I HLA genotyping in East Africa.

PloS one - 20 May 2010

Koehler Rebecca N, Walsh Anne M, Sanders-Buell Eric E, Eller Leigh Anne, Eller Michael, Currier Jeffrey R, Bautista Christian T, Wabwire-Mangen Fred, Hoelscher Michael, Maboko Leonard, Kim Jerome, Michael Nelson L, Robb Merlin L, McCutchan Francine E, Kijak Gustavo H

Abstract excerpt

HLA, the most genetically diverse loci in the human genome, play a crucial role in host-pathogen interaction by mediating innate and adaptive cellular immune responses. A vast number of infectious diseases affect East Africa, including HIV/AIDS, malaria, and tuberculosis, but the HLA genetic diversity in this region remains incompletely described. This is a major obstacle for the design and evaluation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20505773
DOI: 10.1371/journal.pone.0010751
PMCID: PMC2873994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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