Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of human leukocyte antigen alleles as risk factors for cryptococcal disease in Ugandan individuals with HIV.

Human immunology - 1 Aug 2026

Skipper Caleb P, Dai Biyue, Borges Bruno, Augusto Danillo G, Gerlach Elliot, Tukundane Asmus, Tadeo Kiiza, Pastick Katelyn A, Williams Darlisha A, Kabahubya Mable, Rajasingham Radha, Nalintya Elizabeth, Meya David B, Boulware David R, Hollenbach Jill, Nielsen Kirsten

Abstract excerpt

Cryptococcus neoformans is an opportunistic fungal infection and a leading cause of HIV-associated meningitis, contributing significantly to AIDS-related mortality, especially in Africa. Despite advancements in treatment, case fatality rates remain high, emphasizing the need for a better understanding of host immune responses. This study investigated the association between variation in the human leukocyte...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AIDS-Related Opportunistic Infections
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cryptococcosis

Share to Cryptococcus neoformans

Share to HIV Infections

Share to HLA Antigens

Share to Meningitis, Cryptococcal

Share to Uganda

Source

Open in PubMed Open full text

Identifiers

PMID: 42289175
DOI: 10.1016/j.humimm.2026.111788
PMCID: PMC13312324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of human leukocyte antigen alleles as risk factors for cryptococcal disease in Ugandan individuals with HIV.PMID 42289175Read ↗

Full-length next-generation sequencing of 11 HLA loci of more than 1000 individuals from clinical cohorts in East and West AfricaSemantic proximity Read ↗

Full-Length Next-Generation Sequencing of 11 HLA Loci of More Than 1000 Individuals From Clinical Cohorts in East and West Africa.Semantic proximity Read ↗

Analysis of the association of HLA subtypes with cryptococcal meningitis in HIV-negative immunocompetent patients.Semantic proximity Read ↗

Identification of Pathogen Genomic Differences That Impact Human Immune Response and Disease during Cryptococcus neoformans InfectionSemantic proximity Read ↗

Allelic Variation in CNAG_04922 Gene Modulates Host Cytokine Responses during Cryptococcus neoformans InfectionSemantic proximity Read ↗

Identification of pathogen genomic differences that impact human immune response and disease during <i>Cryptococcus neoformans</i> infectionSemantic proximity Read ↗

Cryptococcus neoformans Genotypic Diversity and Disease Outcome among HIV Patients in AfricaSemantic proximity Read ↗

Human immune polymorphisms associated with the risk of cryptococcal disease.Semantic proximity Read ↗

A common human leucocyte antigen-DP genotype is associated with resistance to HIV-1 infection in Kenyan sex workers.Semantic proximity Read ↗

Genotypes coding for mannose-binding lectin deficiency correlated with cryptococcal meningitis in HIV-uninfected Chinese patients.Semantic proximity Read ↗

Clinical epidemiology and high genetic diversity amongst Cryptococcus spp. isolates infecting people living with HIV in Kinshasa, Democratic Republic of Congo.Semantic proximity Read ↗

Immunogenetics of HIV disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.