Article
Detection of recent HIV infections in African individuals infected by HIV-1 non-B subtypes using HIV antibody avidity.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2008
Suligoi Barbara, Buttò Stefano, Galli Claudio, Bernasconi Daniela, Salata Robert A, Tavoschi Lara, Chiappi Michele, Mugyenyi Peter, Pimpinelli Fulvia, Kityo Cissy, Regine Vincenza, Rezza Giovanni
Abstract excerpt
BACKGROUND: To estimate HIV incidence several methods have been used to discriminate recent HIV infections from long-standing infections using a single serum sample. OBJECTIVE: To evaluate the performance of the anti-HIV avidity index (AI) for identifying recent HIV infections in individuals with a known date of seroconversion from Uganda, where the predominant HIV subtypes are A and D. STUDY DESIGN: We selected...
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