Article
Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours.
British journal of cancer - 19 Nov 2007
Carén H, Fransson S, Ejeskär K, Kogner P, Martinsson T
Abstract excerpt
Chromosome 1p is frequently deleted in neuroblastoma (NB) tumours. The commonly deleted region has been narrowed down by loss of heterozygosity studies undertaken by different groups. Based on earlier mapping data, we have focused on a region on 1p36 (chr1: 7 765 595-11 019 814) and performed an analysis of 30 genes by exploring features such as epigenetic regulation, that is DNA methylation and histone...
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