Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Definition and characterization of a region of 1p36.3 consistently deleted in neuroblastoma.

Oncogene - 14 Apr 2005

White Peter S, Thompson Patricia M, Gotoh Takahiro, Okawa Erin R, Igarashi Jun, Kok Marleen, Winter Cynthia, Gregory Simon G, Hogarty Michael D, Maris John M, Brodeur Garrett M

Abstract excerpt

Substantial genomic and functional evidence from primary tumors and cell lines indicates that a consistent region of distal chromosome 1p is deleted in a sizable proportion of human neuroblastomas, suggesting that this region contains one or more tumor suppressor genes. To determine systematically and precisely the location and extent of 1p deletion in neuroblastomas, we performed allelic loss studies of 737...

Topics

Chromosome Deletion
Chromosomes, Human, Pair 1
Cohort Studies
Gene Expression Profiling
Genes, Tumor Suppressor
Genetic Markers
Genotype
Humans
Loss of Heterozygosity
Neuroblastoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Physical Chromosome Mapping

Tumor Cells, Cultured

Source

Identifiers

PMID: 15829979
DOI: 10.1038/sj.onc.1208306

Genes

CHD5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Definition and characterization of a region of 1p36.3 consistently deleted in neuroblastoma.PMID 15829979Read ↗

Expression and sequence analysis of candidates for the 1p36.31 tumor suppressor gene deleted in neuroblastomas.Semantic proximity Read ↗

Identification of a 1-megabase consensus region of deletion at 1p36.3 in primary neuroblastomas.Semantic proximity Read ↗

Smallest region of overlapping deletion in 1p36 in human neuroblastoma: A 1 Mbp cosmid and PAC contigSemantic proximity Read ↗

Identification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line.Semantic proximity Read ↗

Detailed molecular analysis of 1p36 in neuroblastoma.Semantic proximity Read ↗

Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.Semantic proximity Read ↗

Identification of a novel recurrent 1q42.2‐1qter deletion in high risk <i>MYCN</i> single copy 11q deleted neuroblastomasSemantic proximity Read ↗

CHD5 , a Tumor Suppressor Gene Deleted From 1p36.31 in NeuroblastomasSemantic proximity Read ↗

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3.Semantic proximity Read ↗

Integrative Genomics Identifies Distinct Molecular Classes of Neuroblastoma and Shows That Multiple Genes Are Targeted by Regional Alterations in DNA Copy NumberSemantic proximity Read ↗

Mechanisms of CHD5 Inactivation in NeuroblastomasSemantic proximity Read ↗

Constitutional 1p36 deletion in a child with neuroblastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.