Article
Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma.
European journal of cancer (Oxford, England : 1990) - 1 Feb 2007
Henrich Kai-Oliver, Claas Andreas, Praml Christian, Benner Axel, Mollenhauer Jan, Poustka Annemarie, Schwab Manfred, Westermann Frank
Abstract excerpt
Deletion of a distal portion of 1p is seen in a wide range of human malignancies, including neuroblastoma. Here, a 1p36.3 commonly deleted region of 216 kb has been defined encompassing two genes, CAMTA1 and FLJ10737. Low expression of CAMTA1 has been recently shown to be an independent predictor of poor outcome in neuroblastoma patients. The present study surveys CAMTA1 and FLJ10737 for genetic alterations by...
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