Article
Gene expression profiling of 1p35-36 genes in neuroblastoma.
Oncogene - 5 Aug 2004
Janoueix-Lerosey Isabelle, Novikov Eugene, Monteiro Marta, Gruel Nadège, Schleiermacher Gudrun, Loriod Béatrice, Nguyen Catherine, Delattre Olivier
Abstract excerpt
Deletion of the chromosome 1p36 region is a frequent abnormality in neuroblastoma. To gain further insights into the role of this alteration in oncogenesis, we have constructed a specific cDNA microarray representing most known genes and ESTs from the 1p35-36 region and analysed the expression profiles of 15 neuroblastoma cell lines and 28 neuroblastoma tumours. Hierarchical clustering using expression levels of...
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