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Kinetics of cell division in epidermal maintenance

9 Aug 2007

Abstract excerpt

The rules governing cell division and differentiation are central to understanding the mechanisms of development, aging, and cancer. By utilizing inducible genetic labeling, recent studies have shown that the clonal population in transgenic mouse epidermis can be tracked in vivo. Drawing on these results, we explain how clonal fate data may be used to infer the rules of cell division and differentiation...

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Identifiers

PMID: 17930068
DOI: 10.1103/physreve.76.021910

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