Article
A stop-EGFP transgenic mouse to detect clonal cell lineages generated by mutation.
EMBO reports - 1 Sept 2004
Ro Simon, Rannala Bruce
Abstract excerpt
The investigation of cell lineages and clonal organization in tissues is facilitated by techniques that allow labelling of clonal cell lineages. Here, we describe a novel transgenic mouse that allows clonal cell lineages to be traced in virtually any tissue. A green fluorescent cell lineage is generated by a random mutation at an enhanced green fluorescent protein gene that carries a premature stop codon,...
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