Article
The use of genomic information to optimize cancer chemotherapy.
Seminars in oncology - 1 Apr 2011
Innocenti Federico, Cox Nancy J, Dolan M Eileen
Abstract excerpt
The field of pharmacogenomics is focused on the characterization of genetic factors contributing to the response of patients to pharmacological interventions. Drug response and toxicity are complex traits; therefore the effects are likely influenced by multiple genes. The investigation of the genetic basis of drug response has evolved from a focus on single genes to relevant pathways to the entire genome....
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