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From Genes to Personalized Cancer Care: A Systematic Review of Toxicity-Associated Genetic Variants in Solid Tumor Treatments

2025-10-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Pharmacogenomics has emerged as a crucial tool in precision medicine, offering the potential to personalise cancer treatments by predicting and managing therapy-induced toxicities. This systematic review examined the genetic basis of toxicities associated with radiotherapy, chemotherapy, and immunotherapy in solid tumours. <h4>Methods</h4> A comprehensive literature search...

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Literature Corpus work
ba6bc8ae-1ce1-54f0-9cb3-7ee3620d489f
DOI
10.1101/2025.10.21.25338446
Open publication

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