Article
Pharmacogenetics and pharmacogenomics of anticancer agents.
CA: a cancer journal for clinicians - 1 Jan 2000
Huang R Stephanie, Ratain Mark J
Abstract excerpt
Large interindividual variation is observed in both the response and toxicity associated with anticancer therapy. The etiology of this variation is multifactorial, but is due in part to host genetic variations. Pharmacogenetic and pharmacogenomic studies have successfully identified genetic variants that contribute to this variation in susceptibility to chemotherapy. This review provides an overview of the...
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