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Article

Genetic variants in genes involved in mechanisms of chemoresistance to anticancer drugs.

Current cancer drug targets - 1 May 2012

Marin J J G, Briz O, Monte M J, Blazquez A G, Macias R I R

Abstract excerpt

Refractoriness to the pharmacological treatment of cancer is dependent on the expression levels of genes involved in mechanisms of chemoresistance and on the existence of genetic variants that may affect their function. Thus, changes in genes encoding solute carriers may account for considerable inter-individual variability in drug uptake and the lack of sensitivity to the substrates of these transporters....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22229248
DOI: 10.2174/156800912800190875

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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