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Article

Visual DNA -- identification of DNA sequence variations by bead trapping.

Genomics - 1 Dec 2007

Ståhl Patrik L, Gantelius Jesper, Natanaelsson Christian, Ahmadian Afshin, Andersson-Svahn Helene, Lundeberg Joakim

Abstract excerpt

In this paper we describe a method that uses the nearly covalent strength biotin-streptavidin interaction to attach a paramagnetic bead of micrometer size to a DNA molecule of nanometer size, scaling up the spatial size of a query DNA strand by a factor of 1000, making it visible to the human eye. The use of magnetic principles enables rapid binding and washing of detector beads, facilitating a readout of...

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Identifiers

PMID: 17920240
DOI: 10.1016/j.ygeno.2007.07.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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