Article
Product length, dye choice, and detection chemistry in the bead-emulsion amplification of millions of single DNA molecules in parallel.
Analytical chemistry - 15 Jul 2009
Tiemann-Boege Irene, Curtis Christina, Shinde Deepali N, Goodman Daniel B, Tavaré Simon, Arnheim Norman
Abstract excerpt
The amplification of millions of single molecules in parallel can be performed on microscopic magnetic beads that are contained in aqueous compartments of an oil-buffer emulsion. These bead-emulsion amplification (BEA) reactions result in beads that are covered by almost-identical copies derived...
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