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Article

Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments.

Journal of virology - 1 Apr 2003

Wu Thomas D, Schiffer Celia A, Gonzales Matthew J, Taylor Jonathan, Kantor Rami, Chou Sunwen, Israelski Dennis, Zolopa Andrew R, Fessel W Jeffrey, Shafer Robert W

Abstract excerpt

Although many human immunodeficiency virus type 1 (HIV-1)-infected persons are treated with multiple protease inhibitors in combination or in succession, mutation patterns of protease isolates from these persons have not been characterized. We collected and analyzed 2,244 subtype B HIV-1 isolates from 1,919 persons with different protease inhibitor experiences: 1,004 isolates from untreated persons, 637 isolates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12663790
DOI: 10.1128/jvi.77.8.4836-4847.2003
PMCID: PMC152121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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