Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Primary DNA damage and genetic polymorphisms for CYP1A1, EPHX and GSTM1 in workers at a graphite electrode manufacturing plant.

BMC public health - 1 Oct 2007

Moretti Massimo, Dell'Omo Marco, Villarini Milena, Pastorelli Roberta, Muzi Giacomo, Airoldi Luisa, Pasquini Rossana

Abstract excerpt

BACKGROUND: The results of a cross-sectional study aimed to evaluate whether genetic polymorphisms (biomarkers of susceptibility) for CYP1A1, EPHX and GSTM1 genes that affect polycyclic aromatic hydrocarbons (PAH) activation and detoxification might influence the extent of primary DNA damage (biomarker of biologically effective dose) in PAH exposed workers are presented. PAH-exposure of the study populations was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol Side-Chain Cleavage Enzyme
Share to Comet Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1A1

Share to Electrodes

Share to Epoxide Hydrolases

Share to Leukocytes

Share to Occupational Exposure

Share to Pyrenes

Source

Open in PubMed Open full text

Identifiers

PMID: 17908297
DOI: 10.1186/1471-2458-7-270
PMCID: PMC2082035

Genes

PAH
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Primary DNA damage and genetic polymorphisms for CYP1A1, EPHX and GSTM1 in workers at a graphite electrode manufacturing plant.PMID 17908297Read ↗

Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: effects on DNA damage.Semantic proximity Read ↗

Biological indicators of genotoxic risk and metabolic polymorphisms.Semantic proximity Read ↗

Polymorphisms in metabolism and repair genes affects DNA damage caused by open-cast coal mining exposure.Semantic proximity Read ↗

Analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine and DNA strand breaks in white blood cells of occupationally exposed workers: comparison with ambient monitoring, urinary metabolites and enzyme polymorphisms.Semantic proximity Read ↗

Exposure to low environmental levels of benzene: evaluation of micronucleus frequencies and S-phenylmercapturic acid excretion in relation to polymorphisms in genes encoding metabolic enzymes.Semantic proximity Read ↗

CYP1A1 gene polymorphisms: modulator of genetic damage in coal-tar workers.Semantic proximity Read ↗

Variation in PAH-related DNA adduct levels among non-smokers: the role of multiple genetic polymorphisms and nucleotide excision repair phenotype.Semantic proximity Read ↗

Effect of glutathione S-transferase M1 polymorphisms on biomarkers of exposure and effects.Semantic proximity Read ↗

Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair.Semantic proximity Read ↗

Association between genetic polymorphisms and biomarkers in styrene-exposed workers.Semantic proximity Read ↗

Genetic variants of nucleotide excision repair genes are associated with DNA damage in coke oven workers.Semantic proximity Read ↗

Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.