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Article

Genetic variants of nucleotide excision repair genes are associated with DNA damage in coke oven workers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2010

Wang Fang, He Yuefeng, Guo Huan, Li Jichao, Yang Yan, Wu Zhou, Zheng Hongyan, Wu Tangchun

Abstract excerpt

We explored the effects of single nucleotide polymorphisms (SNP) of nucleotide excision repair (NER) genes on DNA damage caused by exposure to carcinogenic polycyclic aromatic hydrocarbons (PAH) in 475 Chinese workers. We quantified urinary 1-hydroxypyrene using high-performance liquid chromatography, and the DNA damage level of lymphocytes was examined by the comet assay and represented as the Olive tail moment...

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Source

Identifiers

PMID: 20056640
DOI: 10.1158/1055-9965.EPI-09-0270

Genes

XPC
PAH
XPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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