Article
Polymorphisms in metabolism and repair genes affects DNA damage caused by open-cast coal mining exposure.
Mutation research. Genetic toxicology and environmental mutagenesis - 15 Sept 2016
Espitia-Pérez Lyda, Sosa Milton Quintana, Salcedo-Arteaga Shirley, León-Mejía Grethel, Hoyos-Giraldo Luz Stella, Brango Hugo, Kvitko Katia, da Silva Juliana, Henriques João A P
Abstract excerpt
Increasing evidence suggest that occupational exposure to open-cast coal mining residues like dust particles, heavy metals and Polycyclic Aromatic Hydrocarbons (PAHs) may cause a wide range of DNA damage and genomic instability that could be associated to initial steps in cancer development and other work-related diseases. The aim of our study was to evaluate if key polymorphisms in metabolism genes CYP1A1Msp1,...
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