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Article

CYP1A1 gene polymorphisms: modulator of genetic damage in coal-tar workers.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Giri Shiv Kumar, Yadav Anita, Kumar Anil, Dev Kapil, Gulati Sachin, Gupta Ranjan, Aggarwal Neeraj, Gautam Sanjeev Kumar

Abstract excerpt

AIM: It is well known that polycyclic aromatic hydrocarbons (PAHs) such as benzo (a) pyrene have carcinogenic properties and may cause many types of cancers in human populations. Genetic susceptibility might be due to variation in genes encoding for carcinogen metabolizing enzymes, such as cytochrome P-450 (CYP450). Our study aimed to investigate the effect of genetic polymorphisms of CYP1A1 (m1 and m2) on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22994769
DOI: 10.7314/apjcp.2012.13.7.3409

Genes

PAH

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