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Article

Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant.

Environmental and molecular mutagenesis - 1 Jan 2004

Vodicka Pavel, Kumar Rajiv, Stetina Rudolf, Musak Ludovit, Soucek Pavel, Haufroid Vincent, Sasiadek Maria, Vodickova Ludmila, Naccarati Alessio, Sedikova Jana, Sanyal Somali, Kuricova Miroslava, Brsiak Viliam, Norppa Hannu, Buchancova Jana, Hemminki Kari

Abstract excerpt

Workers employed in tire plants are exposed to a variety of xenobiotics, such as 1,3-butadiene (BD), soots containing polycyclic aromatic hydrocarbons, and other organic chemicals (e.g., styrene). In the present study, we investigated markers of genotoxicity [chromosomal aberrations (CAs) and single-strand breaks (SSBs)] in a cohort of 110 tire plant workers engaged in jobs with different levels of xenobiotic...

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Identifiers

PMID: 15470755
DOI: 10.1002/em.20055

Genes

EPHX1
GSTM1
GSTP1
GSTT1
SSB
XPC
XRCC1
XRCC3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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