Article
Association between genetic polymorphisms and biomarkers in styrene-exposed workers.
Mutation research - 1 Oct 2001
Vodicka P, Soucek P, Tates A D, Dusinska M, Sarmanova J, Zamecnikova M, Vodickova L, Koskinen M, de Zwart F A, Natarajan A T, Hemminki K
Abstract excerpt
A comprehensive approach to evaluate genotoxic effects induced by styrene exposure was employed in 44 hand-lamination workers in comparison with 18 unexposed controls. The acquired data on single-strand breaks in DNA (SSBs), frequency of chromosomal aberrations and HPRT mutant frequency in peripheral blood lymphocytes were compared to the results on genotyping of some of the xenobiotic-metabolising enzymes...
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