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Article

Variation in PAH-related DNA adduct levels among non-smokers: the role of multiple genetic polymorphisms and nucleotide excision repair phenotype.

International journal of cancer - 15 Jun 2013

Etemadi Arash, Islami Farhad, Phillips David H, Godschalk Roger, Golozar Asieh, Kamangar Farin, Malekshah Akbar Fazel-Tabar, Pourshams Akram, Elahi Seerat, Ghojaghi Farhad, Strickland Paul T, Taylor Philip R, Boffetta Paolo, Abnet Christian C, Dawsey Sanford M, Malekzadeh Reza, van Schooten Frederik J

Abstract excerpt

Polycyclic aromatic hydrocarbons (PAHs) likely play a role in many cancers even in never-smokers. We tried to find a model to explain the relationship between variation in PAH-related DNA adduct levels among people with similar exposures, multiple genetic polymorphisms in genes related to metabolic and repair pathways, and nucleotide excision repair (NER) capacity. In 111 randomly selected female never-smokers...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23175176
DOI: 10.1002/ijc.27953
PMCID: PMC3597757

Genes

PAH
ERCC1
ERCC5
MPO
MTHFR
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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