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Article

Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.

European journal of clinical pharmacology - 1 Dec 2007

Miura Masatomo, Satoh Shigeru, Inoue Kazuyuki, Kagaya Hideaki, Saito Mitsuru, Inoue Takamitsu, Suzuki Toshio, Habuchi Tomonori

Abstract excerpt

OBJECTIVE: We investigated the association between mycophenolic acid (MPA) pharmacokinetics and organic anion-transporting polypeptide (OATP/SLCO)1B1, 1B3, 2B1 and multidrug resistance-association protein 2 (MRP2/ABCC2) genetic polymorphisms and diarrhea. METHODS: Eighty-seven renal allograft recipients were given repeated doses of mycophenolate mofetil every 12 h at a designated time (09:00 and 21:00). The...

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Source

Identifiers

PMID: 17906856
DOI: 10.1007/s00228-007-0380-7

Genes

ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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