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Article

Pharmacokinetic modeling of enterohepatic circulation of mycophenolic acid in renal transplant recipients.

Kidney international - 1 Jun 2014

Colom Helena, Lloberas Núria, Andreu Franc, Caldés Ana, Torras Joan, Oppenheimer Federico, Sanchez-Plumed Jaime, Gentil Miguel A, Kuypers Dirk R, Brunet Mercè, Ekberg Henrik, Grinyó Josep M

Abstract excerpt

Several factors contribute to mycophenolic acid (MPA) between-patient variability. Here we characterize the metabolic pathways of MPA and quantify the effect of combining genetic polymorphism of multidrug-resistant-associated protein-2, demographics, biochemical covariates, co-medication (cyclosporine (CsA) vs. macrolides), and renal function on MPA, 7-O-MPA-glucuronide (MPAG), and acyl-glucuronide (AcMPAG)...

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Identifiers

PMID: 24402086
DOI: 10.1038/ki.2013.517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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