Article
Effect of hepatic drug transporter polymorphisms on the pharmacokinetics of mycophenolic acid in patients with severe renal dysfunction before renal transplantation.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Oct 2017
Kagaya Hideaki, Niioka Takenori, Saito Mitsuru, Inoue Takamitsu, Numakura Kazuyuki, Habuchi Tomonori, Satoh Shigeru, Miura Masatomo
Abstract excerpt
1. The objective of this study was to examine the association of UGT1A9, SLCO, and ABCC polymorphisms with mycophenolic acid (MPA) pharmacokinetics in ABO blood type (ABO) incompatible patients with severe renal dysfunction pre-transplantation. 2. In all patients, on day 14 after beginning mycophenolate mofetil (MMF) treatment (1 week before transplantation) and on day 28 after renal transplantation, samples were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.