Article
Mutations in Ran system affected telomere silencing in Saccharomyces cerevisiae.
Biochemical and biophysical research communications - 23 Nov 2007
Hayashi Naoyuki, Kobayashi Masahiko, Shimizu Hiroko, Yamamoto Ken-ichi, Murakami Seishi, Nishimoto Takeharu
Abstract excerpt
The Ran GTPase system regulates the direction and timing of several cellular events, such as nuclear-cytosolic transport, centrosome formation, and nuclear envelope assembly in telophase. To gain insight into the Ran system's involvement in chromatin formation, we investigated gene silencing at the telomere in several mutants of the budding yeast Saccharomyces cerevisiae, which had defects in genes involved in...
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