HTRA1 variant increases risk to neovascular age-related macular degeneration in Chinese population.

doi:10.1016/j.visres.2007.08.010

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Article

HTRA1 variant increases risk to neovascular age-related macular degeneration in Chinese population.

Vision research - 1 Nov 2007

Lu Fang, Hu Jianbin, Zhao Peiquan, Lin Ying, Yang Yang, Liu Xiaoqi, Fan Yingchuan, Chen Bin, Liao Shihuang, Du Qiong, Lei Chuntao, Cameron D Joshua, Zhang Kang, Yang Zhenglin

Abstract excerpt

Age-related macular degeneration (AMD) is a leading cause of irreversible visual impairment in the world. Advanced AMD can be divided into wet AMD (choroidal neovascularization) and dry AMD (geographic atrophy, GA). Drusen is characterized by deposits in the macula without visual loss and is an early AMD sign in the Caucasian population. rs11200638 in the promoter of HTRA1 has recently been shown to increases the...

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Identifiers

PMID: 17904186
DOI: 10.1016/j.visres.2007.08.010

Genes

HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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