Article
Meta-analysis of the association of the HTRA1 polymorphisms with the risk of age-related macular degeneration.
Experimental eye research - 1 Sept 2009
Chen Wen, Xu Wei, Tao Qiushan, Liu Juan, Li Xiaojing, Gan Xiumin, Hu Honglin, Lu Yunxia
Abstract excerpt
HTRA1 was considered as one of important age-related macular degeneration (AMD) candidate genes. However, due to population heterogeneity and bias from case-control study, the association between HTRA1 and AMD needs further confirmation across different studies in different population. In this study, a meta-analysis was performed in 14 case-control studies which were published before August 31, 2008. Effect of...
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