Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population.

doi:10.1007/s10038-007-0162-1

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Article

Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population.

Journal of human genetics - 1 Jan 2007

Mori Keisuke, Horie-Inoue Kuniko, Kohda Masakazu, Kawasaki Izumi, Gehlbach Peter L, Awata Takuya, Yoneya Shin, Okazaki Yasushi, Inoue Satoshi

Abstract excerpt

The purpose of this investigation was to determine whether the high-temperature requirement A-1 (HTRA1) gene polymorphism is associated with age-related macular degeneration (AMD) in native, unrelated Japanese patients. A total of 123 patients with AMD and 133 control subjects without AMD were recruited for this study. The single-nucleotide polymorphism (SNP) rs11200638 in the HTRA1 gene was assessed using a...

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PMID: 17568988
DOI: 10.1007/s10038-007-0162-1

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HTRA1

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