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Article

HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration.

Molecular vision - 4 Apr 2007

Yoshida Tsunehiko, DeWan Andrew, Zhang Hong, Sakamoto Ryosuke, Okamoto Haru, Minami Masayoshi, Obazawa Minoru, Mizota Atsushi, Tanaka Minoru, Saito Yoshihiro, Takagi Ikue, Hoh Josephine, Iwata Takeshi

Abstract excerpt

PURPOSE: To study the effect of candidate single nucleotide polymorphisms (SNPs) on chromosome 10q26, recently shown to be associated with wet age-related macular degeneration (AMD) in Chinese and Caucasian cohorts, in a Japanese cohort. METHODS: Using genomic DNA isolated from peripheral blood of wet AMD cases and age-matched controls, we genotyped two SNPs, rs10490924, and rs11200638, on chromosome 10q26, 6.6...

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Source

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Identifiers

PMID: 17438519
PMCID: PMC2652018

Genes

HTRA1
CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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