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Article

GPR10 deficiency in mice results in altered energy expenditure and obesity.

Biochemical and biophysical research communications - 23 Nov 2007

Bjursell Mikael, Lennerås Maria, Göransson Melker, Elmgren Anders, Bohlooly-Y Mohammad

Abstract excerpt

In this study, mice carrying a disrupted gene encoding GPR10 (GPR10 KO) were studied to elucidate the function and importance of this receptor regarding metabolism. Female and male GPR10 KO mice had higher body weight after 11 and 15 weeks of age, respectively. The increased body weight was a result of increased fat mass. The obesity was much more pronounced in female mice, which also had a significant decrease...

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Identifiers

PMID: 17904108
DOI: 10.1016/j.bbrc.2007.09.016

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CRH
POMC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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