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GPR41 and GPR43: From development to metabolic regulation

13 May 2024

Abstract excerpt

G-protein-coupled receptors are a diverse class of cell surface receptors that orchestrate numerous physiological functions. The G-protein-coupled receptors, GPR41 and GPR43, sense short-chain fatty acids (SCFAs), which are metabolites of dietary fermentation by the host's intestinal bacteria. These receptors have gained attention as potential therapeutic targets against various diseases because of their...

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PMID: 38744220
DOI: 10.1016/j.biopha.2024.116735

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