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Article

Spontaneously hypertensive rats are highly vulnerable to AMPA-induced brain lesions.

Stroke - 1 Nov 2007

Lecrux Clotilde, Nicole Olivier, Chazalviel Laurent, Catone Christelle, Chuquet Julien, MacKenzie Eric T, Touzani Omar

Abstract excerpt

BACKGROUND AND PURPOSE: Whereas the effects of chronic arterial hypertension on the cerebral vasculature have been widely studied, its effects on brain tissue have been studied less so. Here we examined if spontaneously hypertensive rats (SHRs) or the normotensive control Wistar Kyoto rats (WKYs) made hypertensive by renal artery stenosis (R-WKYs) are vulnerable to an excitotoxic brain lesion provoked by an...

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Source

Identifiers

PMID: 17901379
DOI: 10.1161/STROKEAHA.107.491126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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