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Article

The role of the renin-angiotensin system in malignant vascular injury affecting the systemic and cerebral circulations.

Progress in biophysics and molecular biology - 1 Jan 2000

Collidge Tara A, Lammie G Alistair, Fleming Stewart, Mullins John J

Abstract excerpt

Malignant hypertension is a rare but serious syndrome complicating 1% of essential hypertension and causing neurological, renal and cardiac complications. Despite improved anti-hypertensive medication, the incidence of this condition fails to decline. In the first part of this review, we discuss transgenic rat models of malignant hypertension, generated by over-expressing renin, to illustrate the role of the...

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PMID: 14769441
DOI: 10.1016/j.pbiomolbio.2003.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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