Article
Predisposition to cortical neurodegenerative changes in brains of hypertension prone rats.
Journal of translational medicine - 27 Jan 2023
Ben-Shabat Moti, Awad-Igbaria Yaseen, Sela Shifra, Gross Bella, Yagil Yoram, Yagil Chana, Palzur Eilam
Abstract excerpt
BACKGROUND: Substantial evidence suggests that hypertension is a significant risk factor for cognitive decline. However, it is unclear whether the genetic predisposition to hypertension is also associated with cellular dysfunction that promotes neurodegeneration. METHODS: Changes in blood pressure were evaluated following dietary salt-loading or administration of a regular diet in Sabra Normotensive (SBN/y) and...
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