Article
Genetic variation of the adenylyl cyclase 3 (AC3) locus and its influence on type 2 diabetes and obesity susceptibility in Swedish men.
International journal of obesity (2005) - 1 Mar 2008
Nordman S, Abulaiti A, Hilding A, Långberg E-C, Humphreys K, Ostenson C-G, Efendic S, Gu H F
Abstract excerpt
OBJECTIVE: Our previous study using the Goto-Kakizaki rat implicates that the adenylyl cyclase 3 (AC3) is a candidate gene for genetic study of metabolic disorders. The present study aimed to investigate the susceptibility of genetic variation of the AC3 gene in type 2 diabetes (T2D) patients and obese subjects. SUBJECTS AND METHODS: Variation screening in the putative promoter and validation of single nucleotide...
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